| 64 | Lubomir Cuba (MIDDMT) def. Kevin Ma (AMHM) 6-3, 7-6 (7-4) |
| 64 | Justin Patel (BOWM) def. Jonathan Holtzman (WESM) 6-3, 7-6 (8-6) |
| 64 | Rex Glickman (TCMT1718) def. Vidyut Yadav (BATESM) 6-3, 6-1 |
| 64 | Sachin Raghavan (WILLM) def. Nikhil Das (BRM) 6-3, 6-2 |
| 64 | Alex Vanezis (MIDDMT) def. Zach Bessette (AMHM) 7-5, 3-6, 6-3 |
| 64 | Benjamin Battle (TUFTSM) def. Tom Hackett (CGA) 6-3, 6-1 |
| 64 | Scott Altmeyer (COLBYM) def. Brandon Rosenbluth (BAB) 7-5, 6-3 |
| 64 | Luke Tercek (BOWM) def. Thomas McCorkle (EMERM) 6-0, 6-0 |
| 64 | William de Quant (MIDDMT) def. Larry Zhao (BOWM) 7-6 (7-5), 4-6, 6-3 |
| 64 | Cam Daniels (WESM) def. Alex Romaine (SPR) 3-6, 6-2, 7-5 |
| 64 | J. Aguirre Martinez (WHEM) def. Guilherme Barbosa (NC) 6-4, 7-6 (7-4) |
| 64 | Sean Ko (MIT) def. Danny Coran (TUFTSM) 6-4, 6-2 |
| 64 | Timo van der Geest (MIDDMT) def. Kyle Wolfe (BOWM) 6-2, 6-4 |
| 64 | Andrew Finkelman (WESM) def. Nathan Lookwhy (GC) 6-1, 6-1 |
| 64 | Alex Taylor (WILLM) def. Luke Surawski (WNEM) 6-1, 6-0 |
| 64 | Sean Wei (AMHM) def. Ben Rosen (BATESM) 6-4, 6-3 |
| 64 | Grant Urken (BOWM) def. Josh Quijano (BATESM) 6-2, 6-0 |
| 64 | Boris Sorkin (TUFTSM) def. Alex Wright (CSCM1718) 6-2, 6-3 |
| 64 | Ethan Hillis (AMHM) def. Victor Cheng (MIT) 7-6 (7-4), 6-3 |
| 64 | Brian Grodecki (WILLM) def. Win Smith (WESM) 6-3, 6-4 |
| 64 | Andre Libnic (BAB) def. Justin Wang (BOWM) 6-4, 7-5 |
| 64 | Ananth Raghavan (WILLM) def. David Kalmer (WNEM) 6-3, 6-0 |
| 64 | Anupreeth Coramutla (BRM) def. Court Honda (SPR) 6-3, 6-3 |
| 64 | Noah Farrell (MIDDMT) def. Brandon Howard (NC) 6-0, 6-0 |
| 64 | Tyler Barr (MIT) def. Jacob Eisneberg (BATESM) 5-7, 6-2, 6-3 |
| 64 | Sumukh Pathi (COLBYM) def. Kyle Scheffers (TCMT1718) 6-3, 6-4 |
| 64 | Austin Barr (WILLM) def. John Hu (CGA) 6-2, 6-1 |
| 64 | Zain Ali (TUFTSM) def. Daniel Okin (EMERM) 6-1, 6-0 |
| 64 | Kyle Schlanger (MIDDMT) def. Nick Mathieu (CSCM1718) 6-1, 6-2 |
| 64 | Jackson Kogan (BRM) def. Mason Casady (GC) 6-2, 6-1 |
| 64 | Calvin Chung (WILLM) def. Nathan Kaplan (AMHM) 6-2, 6-0 |
| 64 | Steven Chen (WESM) def. J. Esteban de Celis (WHEM) 6-0, 6-1 |
| 32 | Lubomir Cuba (MIDDMT) def. Justin Patel (BOWM) 6-4, 7-5 |
| 32 | Sachin Raghavan (WILLM) def. Rex Glickman (TCMT1718) 6-4, 6-2 |
| 32 | Alex Vanezis (MIDDMT) def. Benjamin Battle (TUFTSM) 6-3, 5-7, 6-3 |
| 32 | Luke Tercek (BOWM) def. Scott Altmeyer (COLBYM) 6-1, 6-3 |
| 32 | William de Quant (MIDDMT) def. Cam Daniels (WESM) 6-4, 7-5 |
| 32 | Sean Ko (MIT) def. J. Aguirre Martinez (WHEM) 6-2, 6-4 |
| 32 | Andrew Finkelman (WESM) def. Timo van der Geest (MIDDMT) 6-3, 6-0 |
| 32 | Sean Wei (AMHM) def. Alex Taylor (WILLM) 6-7 (5-7), 6-3, 6-2 |
| 32 | Boris Sorkin (TUFTSM) def. Grant Urken (BOWM) 4-1, retired |
| 32 | Brian Grodecki (WILLM) def. Ethan Hillis (AMHM) 6-4, 7-6 (7-5) |
| 32 | Ananth Raghavan (WILLM) def. Andre Libnic (BAB) 6-1, 6-0 |
| 32 | Noah Farrell (MIDDMT) def. Anupreeth Coramutla (BRM) 6-3, 6-1 |
| 32 | Sumukh Pathi (COLBYM) def. Tyler Barr (MIT) 7-6 (7-4), retired |
| 32 | Austin Barr (WILLM) def. Zain Ali (TUFTSM) 6-0, 2-6, 6-4 |
| 32 | Kyle Schlanger (MIDDMT) def. Jackson Kogan (BRM) 6-2, 6-4 |
| 32 | Steven Chen (WESM) def. Calvin Chung (WILLM) 6-4, 6-0 |
| 16 | Lubomir Cuba (MIDDMT) def. Sachin Raghavan (WILLM) 6-3, 6-7 (6-8), 6-3 |
| 16 | Luke Tercek (BOWM) def. Alex Vanezis (MIDDMT) 6-2, 6-3 |
| 16 | William de Quant (MIDDMT) def. Sean Ko (MIT) 7-6 (7-5), 6-3 |
| 16 | Andrew Finkelman (WESM) def. Sean Wei (AMHM) 6-2, 5-7, 6-2 |
| 16 | Brian Grodecki (WILLM) def. Boris Sorkin (TUFTSM) 7-5, 7-6 (9-7) |
| 16 | Noah Farrell (MIDDMT) def. Ananth Raghavan (WILLM) 7-5, 6-1 |
| 16 | Austin Barr (WILLM) def. Sumukh Pathi (COLBYM) 6-2, 6-0 |
| 16 | Steven Chen (WESM) def. Kyle Schlanger (MIDDMT) 6-3, 6-2 |
| QF | Lubomir Cuba (MIDDMT) def. Luke Tercek (BOWM) 6-2, 6-0 |
| QF | Andrew Finkelman (WESM) def. William de Quant (MIDDMT) 6-2, 6-2 |
| QF | Brian Grodecki (WILLM) def. Noah Farrell (MIDDMT) 6-3, 6-3 |
| QF | Austin Barr (WILLM) def. Steven Chen (WESM) 7-5, 6-3 |
| SF | Andrew Finkelman (WESM) def. Lubomir Cuba (MIDDMT) 6-2, 6-3 |
| SF | Brian Grodecki (WILLM) def. Austin Barr (WILLM) 7-5, 6-7 (5-7), 6-4 |
| F | Brian Grodecki (WILLM) def. Andrew Finkelman (WESM) 6-2, 6-4 |
